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Category:
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7TM Receptors Acetylcholine (Muscarinic) ReceptorsAgonists
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Cat.No.
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Product Name
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1384 |
McN-A 343
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Price and Availability
Click here for full price details of
McN-A 343
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Chemical Name:
4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethy
l-2-butyn-1-aminium chloride |
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Biological Activity:
Selective
muscarinic M1 receptor agonist. Selectivity for M1 over
other muscarinic receptor types appears to arise from a high efficacy at M1
receptors.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Micheletti
and Schiavone (1990)
Functional determination of McN-A-343 affinity for M1 muscarinic
receptors. J.Pharmacol.Exp.Ther. 253 310. Eglen et al
(1996) Muscarinic receptor subtypes and smooth muscle function. Pharmacol.Rev.
48 531. Davies et al (2001) Inhibition of field
stimulation-induced contractions of rabbit vas deferens by muscarinic receptor
agonists: selectivity of McN-A-343 for M1 receptors.
J.Pharm.Pharmacol. 53 487.
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View related products by Pharmacological Action
or by Research Area
Keywords: McN-A 343, Acetylcholine (Muscarinic) Receptors, Selective M1 Muscarinic Agonist, McNA 343, Tocris Bioscience
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Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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