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Category: 7TM ReceptorsarrowP2Y ReceptorsarrowAntagonists
Cat.No. Product Name
2402 MRS 2211
Price and Availability

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MRS 2211
Chemical Name: 2-[(2-Chloro-5-nitrophenyl)azo]-5-hydroxy-6-methyl-3-[( phosphonooxy)methyl]-4-pyridinecarboxaldehyde disodium salt

Biological Activity:

Competitive P2Y13 receptor antagonist (pIC50 = 5.97) that displays > 20-fold selectivity over P2Y1 and P2Y12 receptors.

Technical Data:

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M.Wt: 474.66
Formula: C14H10N4O8Na2PCl
Storage: Desiccate at -20°C
Solubility: Soluble to 70 mM in Water

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Kim et al (2005) Synthesis of pyridoxal phosphate derivatives with antagonist activity at the P2Y13 receptor. Biochem.Pharmacol. 70 266. Kugelgen (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol.Ther. 110 415.
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    Keywords: MRS 2211, P2Y Receptors, Competitive P2Y13 Antagonist, MRS2211, Tocris Bioscience

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