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Category: Cellular Processes and ComponentsarrowCell MetabolismarrowNeuronal Metabolism
Cat.No. Product Name
2568 MOG (35-55)
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MOG (35-55)

Biological Activity:

Myelin oligodendrocyte glycoprotein (MOG) 35-55 is a minor component of CNS myelin. Produces a relapsing-remitting neurological disease with extensive plaque-like demyelination, common to the manifestations of multiple sclerosis. Induces strong T and B cell responses and is highly encephalitogenic.

Technical Data:

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M.Wt: 2581.97
Formula: C118H177N35O29S
Storage: Desiccate at -20°C
CAS No: [149635-73-4]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Ichikawa et al (1996) Analysis of the fine B cell specificity during the chronic/relapsing course of a multiple sclerosis-like disease in Lewis rats injected with the encephalitogenic myelin oligodendrocyte glycoprotein peptide 35-55. J.Immunol. 157 919. Slavin et al (1998) Induction of a multiple sclerosis-like disease in mice with an immunodominant epitope of myelin oligodendrocyte glycoprotein. Autoimmunity 28 109. Zhang et al (2004) T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6xSJL) F1 mice. J.Neuroimmunol. 148 1.
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    Keywords: MOG (35-55), Cell Metabolism, Encephalitogenic Myelin Oligodendrocyte Glycoprotein Fragment, MOG(35-55), Tocris Bioscience

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