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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowIon Channel
Cat.No. Product Name
0955 (-)-MK 801 maleate  
Price and Availability

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(-)-MK 801 maleate
Chemical Name: (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylc ohepten-5,10-imine maleate

Biological Activity:

Less active enantiomer (10-fold less potent in behavioural studies) than (+)-MK 801 maleate (Cat. No. 0924).

Technical Data:

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M.Wt: 337.37
Formula: C16H15N.C4H4O4
Storage: Store at RT
Solubility: Soluble to 25 mM in Water
Purity: >99%
CAS No: [77086-19-2]

Resources:

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    • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch

    References:

    Thompson et al (1990) Synthesis and pharmacological evaluation of a series of dibenzo[a,d]cycloalkenimines as N-Methyl-D-aspartate antagonists. J.Med.Chem. 33 789. Genovese and Lu (1991) Effects of MK-801 stereoisomers on schedule-controlled behavior in rats. Psychopharmacology. 105 477.
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    Keywords: (-)-MK 801 Maleate, Ligand-gated Ion Channels, NMDA Antagonist, Less Active Enantiomer, MK801 Maleate, Tocris Bioscience
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