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Category:
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7TM Receptors Leukotriene Receptors
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Cat.No.
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Product Name
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2307 |
Leukotriene B4
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| Alternative name(s): |
LTB4 |
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5,12-DiHETE |
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Price and Availability
Click here for full price details of
Leukotriene B4
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Chemical Name:
(5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxy-6,8,10,14-eicosat
etraenoic acid |
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Biological Activity:
Potent
lipid inflammatory mediator derived from the 5-lipoxygenase pathway of
arachidonic acid metabolism. Binds to BLT1 and BLT2
receptors and acts as a potent chemotactic agent and activator of leukocytes.
Also displays antiviral activity towards DNA viruses and retroviruses.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Bray et al (1981) Leukotriene B4: an inflammatory mediator in
vivo. Prostaglandins 22 213. Ford-Hutchinson (1990)
Leukotriene B4 in inflammation. Crit.Rev.Immunol. 10 1. Yokomitso
et al (2001) Leukotriene B4: metabolism and signal
transduction. Arch.Biochem.Biophys. 385 231.
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or by Research Area
Keywords: Leukotriene B4, Leukotriene Receptors, BLT1 / BLT2 Receptor Agonist & Potent Chemotactic Factor, LTB4, 5,12-DiHETE, Tocris Bioscience
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