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Category: Cellular Processes and ComponentsarrowSignal TransductionarrowInositol and cAMP SignallingarrowInositol Lipids
Cat.No. Product Name
0682 L-690,488
Price and Availability

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L-690488

Other Information:

Sold with the permission of Merck Sharp and Dohme Ltd
Chemical Name: 1-[(4-Hydroxyphenoxy)ethylidene]bis[phosphinylidynebis( oxymethylene)]-2,2-dimethylpropanoate

Biological Activity:

Cell-permeable prodrug of the potent inositol monophosphatase inhibitor L-690,330 (Cat. No. 0681); penetrates cells more effectively than its metabolite.

Technical Data:

Click here for more information on batch specific data
M.Wt: 754.7
Formula: C32H52O16P2
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in Ethanol and to 100 mM in DMSO
CAS No: [142523-14-6]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Atack et al (1994) Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers. J.Pharmacol.Exp.Ther. 270 70. Chen et al (1998) Stimulatory effect of lithium on glucose transport in rat adipocytes is not mediated by elevation of IP1. Am.J.Physiol. 275 E272.
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    Keywords: L-690488, Signal Transduction, Cell Permeable Prodrug Of The IMPase Inhibitor L-690,330 (Cat. No. 0681), L690488, Tocris Bioscience

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