Isamoltane Hemifumarate | 5-HT Receptors | 5-HT1B Antagonist

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Cat.No.	Product Name
0992	Isamoltane hemifumarate

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Isamoltane hemifumarate

Chemical Name: 1-[(1-Methylethyl)amino]-3-[2-(1H-pyrrol-1-yl)]-propan- 2-ol hemifumarate

Biological Activity:

5-HT_1B antagonist, approximately 30-fold selective over 5-HT_1A. Also possesses affinity for β-adrenergic receptors.

Technical Data:

M.Wt:	332.4
Formula:	C₁₆H₂₂N₂O₂.½C₄H₄O₄
Storage:	Desiccate at +4°C
Solubility:	Soluble to 10 mM in Water
CAS No:	[55050-95-8]

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Certificate of Analysis / MSDS:

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References:

Waldmeier et al (1988) Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT₁ receptor subtypes in the rat brain. Naunyn-Schmied.Arch.Pharmacol. 337 609.

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Keywords: Isamoltane Hemifumarate, 5-HT Receptors, 5-HT1B Antagonist, Tocris Bioscience

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5-HT Receptors & their Ligands
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