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Imiloxan hydrochloride
Other Information:
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with the permission of Roche Bioscience
Chemical Name:2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan
hydrochloride
Biological Activity:
A moderately potent, but highly selective α2-adrenoceptor antagonist,
the only reported selective antagonist at the α2B-adrenoceptor not having
potent α1-adreonceptor antagonist
activity.
Michel and Whiting (1981) 2-(2-Imidazolylmethyl)-1,4-benzodioxans,
a series of selective alpha2-adrenoceptor antagonists.
Br.J.Pharmacol. 74 255P. Michelet al (1990)
Assessment of imiloxan as a selective α2B-adrenoceptor antagonist.
Br.J.Pharmacol. 99 560.
