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Category: 7TM ReceptorsarrowPeptides (Neuropeptides)arrowTachykinin ReceptorsarrowNK-1 Receptor
Cat.No. Product Name
2576 Hemokinin 1 (human)
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Hemokinin 1 (human)

Biological Activity:

Endogenous substance P homologue that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM respectively). Has proliferative and anti-apoptotic actions on B-cells in vitro and is antihypertensive in vivo.

Technical Data:

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M.Wt: 1185.4
Formula: C54H84N14O14S
Storage: Desiccate at -20°C
CAS No: [491851-53-7]

Resources:

  • Certificate of Analysis / MSDS:

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    References:

    Zhang et al (2000) Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nature Immunol. 1 392. Bellucci et al (2002) Pharmacological profile of the novel mammalian tachykinin hemokinin 1. Br.J.Pharmacol. 135 266. Kurtz et al (2002) Identification, localization and receptor characterization of novel mammalian substance P-like peptides. Gene 296 205.
    View related products by Pharmacological Action or by Research Area

    Keywords: Hemokinin 1 (human), Peptides (Neuropeptides), Endogenous, Selective NK1 Agonist, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Tachykinin Receptor Compounds
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