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Category:
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7TM Receptors Dopamine ReceptorsD2-like ReceptorsAntagonists
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Cat.No.
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Product Name
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0931 |
Haloperidol hydrochloride
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Price and Availability
Click here for full price details of
Haloperidol hydrochloride
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Chemical Name:
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-flu
orophenyl)-1-butanone hydrochloride |
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Biological Activity:
Dopamine antagonist with selectivity
for D2-like receptors (Ki values are 1.2, ~ 7, 2.3, ~ 80
and ~ 100 nM for D2, D3, D4, D1 and
D5 receptors respectively). Subtype selective NMDA antagonist.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Merck Index 12 4629.
Beresford and Ward (1987) Haloperidol decanoate. A preliminary review of
its pharmacodynamic and pharmacokinetic properties and therapeutic use in
psychosis. Drugs 33 31. Seeman and
Van Tol (1994) Dopamine receptor pharmacology. TiPS 15
264. Lynch
and Gallagher (1996) Inhibition of N-methyl-D-aspartate receptors by
haloperidol: development and pharmacological characterization in native and
recombinant receptors. J.Pharmacol.Exp.Ther. 279 154. IIyin
et al (1996) Subtype-selective inhibition of N-methyl-D-aspartate
receptors by haloperidol. Mol.Pharmacol. 50 1541.
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View related products by Pharmacological Action
or by Research Area
Keywords: Haloperidol Hydrochloride, Dopamine Receptors, Antagonist, Partly D2 Selective , Tocris Bioscience
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Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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