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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowKainate SelectivearrowOther
Cat.No. Product Name
2048 Anti-GluR6/7
(Rabbit polyclonal IgG)
Immunoblot IB: Rat brain homogenate probed with anti-GluR6/7 (2 μg/ml)
Price and Availability

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GluR6 / 7, Anti-

Specificity and cross reactivity:

Recognises rat GluR6 and rat GluR7; migrates at a band of ~ 115 kDa. Also predicted to cross-react with mouse and human homologues.

Immunogen:

KLH conjugated synthetic peptide ([C]-HTFNDRRLPGKETMA) corresponding to the C-terminus amino acids 894-908 of rat precursor GluR6 (Accession No. P42260). This sequence is 85% identical to rat GluR7. 50 μg of immunogen is provided with the antibody as a blocking peptide and can also be purchased separately (Cat. No. 2113).

Applications:

IB

Resources:

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    Certificate of Analysis / MSDS:

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    No Product/Material Safety Data Sheet available.
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    References:

    Agrawal and Fehlings (1997) Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury. J.Neurosci. 17 1055. Brandstatter et al (1997) Selective synaptic distribution of kainate receptor subunits in the two plexiform layers of the rat retina. J.Neurosci. 17 9298. Mulle et al (1998) Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice. Nature 392 601.
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    Keywords: GluR6 / 7, Anti-, Ligand-gated Ion Channels, Antibody Recognising Rat GluR6 & GluR7 Subunits, Tocris Bioscience
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