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Category:
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7TM Receptors Peptides (Gastrointestinal)Ghrelin Receptors
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Cat.No.
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Product Name
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2951 |
[Des-octanoyl]-Ghrelin (rat)
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Non-acylated ghrelin (rat) |
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Des-acyl ghrelin (rat) |
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Price and Availability
Click here for full price details of
[des-octanoyl]-Ghrelin (rat)
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Biological Activity:
Non-acylated, major circulating isoform of ghrelin that does not
bind to the growth hormone secretagogue (GHS) receptor, nor induce growth
hormone release.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Baldanzi et al (2002) Ghrelin and
des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells
through ERK1/2 and PI 3-kinase/AKT. J.Cell Biol. 159 1029. Bedendi
et al (2003) Cardiac effects of ghrelin and its endogenous derivatives
des-octanoyl ghrelin and des-Gln14-ghrelin. Eur.J.Pharmacol. 476
87. Thompson et al (2004) Ghrelin and des-octanoyl ghrelin
promote adipogenesis directly in vivo by a mechanism independent of the
type 1a growth hormone secretagogue receptor. Endocrinology 145
234. Cassoni et al (2004) Expression of ghrelin and biological
activity of specific receptors for ghrelin and des-acyl ghrelin in human
prostate neoplasms and related cell lines. Eur.J.Endocrinol. 150
173.
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Keywords: [des-octanoyl]-Ghrelin (rat), Peptides (Gastrointestinal), Major Circulating Form Of Ghrelin; Devoid Of Activity At GHS Receptor, Non-acylated Ghrelin (rat), Des-acyl Ghrelin (rat), Tocris Bioscience
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| “Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..” Researcher, University of Aberdeen, UK |
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