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Category:
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7TM Receptors Cannabinoid ReceptorsCB2 Receptors
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Cat.No.
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Product Name
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2764 |
GP 1a
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Price and Availability
Click here for full price details of
GP 1a
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Chemical Name:
N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6
-methylindeno[1,2-c]pyrazole-3-carboxamide |
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Biological Activity:
Highly selective CB2 receptor
agonist; Ki values are 0.037 and 363 nM for CB2 and CB1
receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Murineddu et al
(2006) Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues
of the robust and selective CB2 cannabinoid ligand
1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide.
J.Med.Chem. 49 7502.
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Keywords: GP 1a, Cannabinoid Receptors, Highly Selective CB2 Agonist, GP1a, Tocris Bioscience
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