|
Category:
|
7TM Receptors Peptides (Cardiovascular)PAR Receptors
|
|
|
Biological Activity:
Potent and selective PAR2 receptor
agonist (pD2 = 7.0). Causes a dose-dependent relaxation of murine
femoral arteries.
|
Technical Data:
|
|
|
Resources:
|
|
Certificate of Analysis / MSDS:
|
References:
McGuire et al
(2004) 2-Furoyl-LIGRLO-amide: a potent and selective proteinase-activated
receptor 2 agonist. J.Pharmacol.Exp.Ther. 309 1124. Alshurafa et al (2004) A
protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH2,
induces protease release from mast cells: role in TNF degradation. BMC
Pharmacol. 4 12. Olianas et al (2007)
Proteinase-activated receptors 1 and 2 in rat olfactory system: layer-specific
regulation of multiple signaling pathways in the main olfactory bulb and
induction of neurite retraction in olfactory sensory neurons. Neuroscience 146
1289.
|
|
View related products by Pharmacological Action
or by Research Area
Keywords: 2-Furoyl-LIGRLO-amide, Peptides (Cardiovascular), Potent & Selective PAR2 Agonist, 2Furoyl-LIGRLO-amide, Tocris Bioscience
|
|
First-Class Technical Expertise
At Tocris we understand that planning an experiment is complicated and that it is important to be able to interact with knowledgeable people who care about helping you find the products and information you need.
Our specialist scientists provide the highest level of service for every enquiry, fully researching each one and supplying the most accurate response, quickly.
We encourage our customers to contact us; no question is too small or insignificant.
|
|
