|
Category:
|
Ion Channels Sodium ChannelsVoltage-gated Sodium Channels
|
|
Cat.No.
|
Product Name
|
|
1470 |
Flecainide acetate
|
|
|
|
Price and Availability
Click here for full price details of
Flecainide acetate
|
|
Chemical Name:
N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)be
nzamide acetate |
|
|
Biological Activity:
Open Na+ channel blocker that
inhibits fast Na+ current in cardiac muscle in a use- and
concentration-dependent manner. Orally-active class Ic antiarrhythmic agent.
|
Technical Data:
|
|
|
Resources:
|
|
Certificate of Analysis / MSDS:
|
References:
Banitt et al
(1977) Antiarrhythmics. 2. Synthesis and antiarrhythmic activity of N-(piperidylalkyl)trifluoroethoxybenzamides.
J.Med.Chem. 20 821. Singh et al (1984) The
electrophysiology and pharmacology of verapamil, flecainide, and amiodarone:
correlations with clinical effects and antiarrhythmic actions.
Ann.N.Y.Acad.Sci. 17 251. Rouet and Ducouret (1994)
Use-and concentration-dependent effects of flecainide in guinea pig right
ventricular muscle. J.Cardiovasc.Pharmacol. 24 177.
|
|
View related products by Pharmacological Action
or by Research Area
Keywords: Flecainide Acetate, Sodium Channels, Cardiac Na+ Channel Blocker. Antiarrhythmic, Tocris Bioscience
|
|
Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
|
