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Category:
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7TM Receptors Dopamine ReceptorsD1-like Receptors
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Cat.No.
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Product Name
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1659 |
Fenoldopam hydrochloride
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| Alternative name(s): |
SKF 82526 |
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Price and Availability
Click here for full price details of
Fenoldopam
Other Information:
Sold for
research purposes under agreement from GlaxoSmithKline
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Chemical Name:
6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-be
nzazepine-7,8-diol hydrochloride |
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Biological Activity:
Selective
D1-like dopamine receptor partial agonist (EC50 = 57 nM).
Vasodilator in vivo and does not readily cross the blood-brain barrier. Also α2-adrenoceptor antagonist in vitro (Ki
= 15-25 nM).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Hahn et al (1982)
Characterization of the peripheral and central effects of SK&F 82526, a
novel dopamine receptor agonist. J.Pharmacol.Exp.Ther. 223 305. Sibley
et al (1982) Interactions of novel dopaminergic ligands with D-1 and D-2
dopamine receptors. Life Sci. 31 637. Nichols et al
(1990) The pharmacology of fenoldopam. Am.J.Hypertens. 3 116S.
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View related products by Pharmacological Action
or by Research Area
Keywords: Fenoldopam, Dopamine Receptors, Selective D1-like Partial Agonist, SKF 82526, Tocris Bioscience
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Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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