Etazolate Hydrochloride | Phosphodiesterases | PDE4 Inhibitor

Category:

Cat.No.	Product Name
0438	Etazolate hydrochloride

Price and Availability

Click here for full price details of
Etazolate hydrochloride

Chemical Name: 1-Ethyl-4-[(1-methylethylidene)hydrazino]-1H-pyrazolo-[ 3,4-b]-pyridine-5-carboxylic acid, ethyl ester hydrochloride

Biological Activity:

Phosphodiesterase inhibitor, selective for PDE4 (IC₅₀ = 2.0 μM).

Technical Data:

M.Wt:	325.8
Formula:	C₁₄H₁₉N₅O₂.HCl
Storage:	Store at RT
Solubility:	Soluble to 50 mM in Water
CAS No:	[51022-77-6]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Chesin et al (1972) 1-Ethyl-4-(isopropylidenehydrazinol-H-pyrazolo-(3,4-b)-pyridin-5-carboxylic acid, ethyl ester, hydrochloride (SQ 20009) - potent new inhibitor of cyclic 3'5-nucleotide phosphodiesterase. Biochem.Pharmacol. 21 2443. Rhoads (1982) Selective inhibition of cyclic AMP and cyclic GMP phosphodiesterases of cardiac nuclear fraction. Biochem.Pharmacol. 31 665. Ahluwalia and Nicholson et al (1991) Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes. TiPS 12 19.

View related products by Pharmacological Action or by Research Area

Keywords: Etazolate Hydrochloride, Phosphodiesterases, PDE4 Inhibitor, Tocris Bioscience

Literature in this Area

Signal Transduction Guide

	A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
View PDF

Unique & Diverse Compound Libraries

Tocriscreen Collections : For pricing and compound information click here

Fully annotated small molecule libraries for HTS, HCS and
chemical biology applications.

1120 compounds
Pre-dissolved in DMSO

Tocriscreen Total (250 μL/well)
Tocriscreen Mini (50 μL/well)

New Products in this Area

	3056	Pentoxifylline
	PDE inhibitor
	2845	IBMX
	PDE inhibitor (non-selective)

for new product e-alerts

User ID
Password