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Category: Nuclear ReceptorsarrowEstrogen and Related Receptors
Cat.No. Product Name
2823 a-Estradiol
Price and Availability

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Estradiol, alpha
Chemical Name: (17a)-Estra-1,3,5(10)-triene-3,17-diol

Biological Activity:

Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).

Technical Data:

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M.Wt: 272.38
Formula: C18H24O2
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO and to 100 mM in Ethanol
Purity: >96%
CAS No: [57-91-0]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Kuiper et al (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinol. 138 863. Toran-Allerand et al (2002) ER-X: a novel, plasma membrane-associated, putative estrogen receptor that is regulated during development and after ischemic brain injury. J.Neurosci. 22 8391.
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    Keywords: Estradiol, Alpha, Estrogen & Related Receptors, Endogenous Estrogen Receptor Ligand, Tocris Bioscience

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    Product Feature
    Estrogen Receptors
    Key estrogen receptors available from Tocris include:
    2662   PHTPP
    Selective ERβ antagonist
    2676   Y 134
    Selective estrogen receptor modulator
    2183   ZK 164015
    Potent estrogen receptor silent antagonist
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     2824β-Estradiol
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     2662PHTPP
     Selective ERβ antagonist
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