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Category: 7TM ReceptorsarrowProstanoid Receptors
Cat.No. Product Name
2989 Epoprostenol
Alternative name(s): Prostaglandin I2
Prostacyclin
Price and Availability

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Epoprostenol
Chemical Name: (5Z,13E,8R,9S,11R,12R,15S)-6,9-Epoxy-11,15-dihydroxypro sta-5,13-dien-1-oic acid sodium salt

Biological Activity:

Endogenous prostanoid that is a potent agonist at IP prostanoid receptors. Inhibits platelet aggregation and induces vasodilation.

Technical Data:

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M.Wt: 374.45
Formula: C20H31NaO5
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in Water and to 75 mM in DMSO
Purity: >99%
CAS No: [61849-14-7]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Oliva and Nicosia (1987) PGI2-receptors and molecular mechanisms in platelets and vasculature: state of the art. Pharmacol.Res.Comm. 19 735. Kobzar et al (2001) Comparison of anti-aggregatory effects of PGI2, PGI3 and iloprost on human and rabbit platelets. Cell.Physiol.Biochem. 11 279.
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    Keywords: Epoprostenol, Prostanoid Receptors, Endogenous IP Receptor Agonist, Prostaglandin I2, Prostacyclin, Tocris Bioscience

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