Endomorphin-1 | Opioid Receptors | Potent & Selective M Agonist

Category:

Cat.No.	Product Name
1055	Endomorphin-1

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Endomorphin-1

Biological Activity:

Endogenous peptide with an exceptionally high affinity (K_i = 360 pM) and selectivity for m opioid receptors (4000- and 15000-fold preference over δ and κ respectively).

Technical Data:

M.Wt:	610.67
Formula:	C₃₄H₃₈N₆O₅
Storage:	Desiccate at -20°C
CAS No:	[189388-22-5]

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References:

Zadina et al (1997) A potent and selective endogenous agonist for the µ-opiate receptor. Nature 386 499. Kakizawa et al (1997) Parallel stimulations of in vitro and in situ [³⁵S]GTPγS binding by endomorphin 1 and DAMGO in mouse brains. Peptides 19 755. Harrison et al (1998) Differential effects of endomorphin-1, endomorphin-2, and tyr-W-MIF-1 on activation of G-proteins in SH-SY5Y human neuroblastoma membranes. Peptides 19 749. Goldberg et al (1998) Pharmacological characterization of endomorphin-1 and endomorphin-2 in mouse brain. J.Pharmacol.Exp.Ther. 286 1007.

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Keywords: Endomorphin-1, Opioid Receptors, Potent & Selective M Agonist, Tocris Bioscience

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Opioid Receptors
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