EGLU | Glutamate (Metabotropic) Receptors | Highly Selective Group II MGlu Antagonist

Category:

Cat.No.	Product Name
0971	EGLU

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EGLU

Chemical Name: (2S)-a-Ethylglutamic acid

Biological Activity:

Selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneurone excitation in neonatal rat spinal cord; presumed group II mGlu receptor antagonist.

Technical Data:

M.Wt:	175.18
Formula:	C₇H₁₃NO₄
Storage:	Store at RT
Solubility:	Soluble to 100 mM in 1eq. NaOH

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References:

Thomas et al (1996) (S)-α-Ethylglutamic acid and (RS)-α-cyclopropyl-4-phosphonophenylglycine as antagonists of L-AP4- and (1S,3S)-ACPD-induced depression of monosynaptic excitation of neonatal rat motoneurones. Br.J.Pharmacol. 117 70P. Jane et al (1996) Potent antagonists at L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate recpetors in neonatal rat spinal cord. Neuropharmacology 35 1029.

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Keywords: EGLU, Glutamate (Metabotropic) Receptors, Highly Selective Group II MGlu Antagonist, Tocris Bioscience

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