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Dilazep dihydrochloride
Chemical Name:1,4-bis[3-(3,4,5-Trimethoxybenzoyloxy)propyl]homopipera
zine dihydrochloride
Biological Activity:
Coronary and cerebral vasodilator, suppresses the effects of
ischemia. Inhibitor of platelet aggregation and of membrane transport of
nucleosides. Inhibits adenosine uptake.
Zhang et al (1991) Dilazep potentation of adenosine-mediated superior
mesenteric arterial vasodilation. J.Pharmacol.Exp.Ther. 258 767. Kawagoeet al (1992) Effect of dilazep dihydrochloride against ischemia and
reperfusion-induced disruption of blood-brain barrier in rats: a quantitative
study. Naunyn-Schmied.Arch.Pharmacol. 345 485.