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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAntagonists
Cat.No. Product Name
3071 Dextromethorphan hydrobromide
Price and Availability

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Dextromethorphan hydrobromide
Chemical Name: (9a,13a,14a)-3-Methoxy-17-methylmorphinan hydrobromide

Biological Activity:

Non-competitive, low affinity NMDA receptor antagonist. Antitussive, anticonvulsive and neuroprotective agent.

Technical Data:

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M.Wt: 352.31
Formula: C18H25NO.HBr
Storage: Store at RT
Solubility: Soluble to 40 mM in Water
Purity: >99%
CAS No: [6700-34-1]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Choi et al (1987) Dextrorophan and levorphanol  selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on corticol neurons. J.Pharmacol.Exp.Ther. 242 713. Keller et al (2008) Dextromethorphan is protective against sensitized N-methyl-D-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain. Eur.J.Neurosci. 27 874.
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    Keywords: Dextromethorphan Hydrobromide, Ligand-gated Ion Channels, NMDA Receptor Antagonist, Tocris Bioscience
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