Tocris Bioscience
Welcome to Tocris

| Advanced Search
Home Products Technical Support Customer Support Literature Custom Synthesis
Category: 7TM ReceptorsarrowPeptides (Gastrointestinal)arrowCCK Receptors
Cat.No. Product Name
2304 Devazepide
Alternative name(s): L-364,718
MK 329
Price and Availability

Click here for full price details of
Devazepide

Biological Activity:

Potent, orally active CCK1 (CCK-A) receptor antagonist that displays appetite-stimulant effects. Blocks the anorectic response to CCK-8 and increases food intake in rats following systemic and i.c.v administration.

Technical Data:

Click here for more information on batch specific data
M.Wt: 408.46
Formula: C25H20N4O2
Storage: Store at +4°C
Solubility: Soluble to 100 mM in DMSO and to 50 mM in Ethanol
Purity: >99%
CAS No: [103420-77-5]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Ebenezer (2002) Effects of intracerebroventricular administration of the CCK1 receptor antagonist devazepide on food intake in rats. Eur.J.Pharmacol. 441 79. Reidelberger et al (2003) Effects of peripheral CCK receptor blockade on food intake in rats. Am.J.Physiol.Reg.Integr.Comp.Physiol. 285 R429. Ritter (2004) Increased food intake and CCK receptor antagonists: beyond abdominal vagal afferents. Am.J.Physiol.Reg.Integr.Comp.Physiol. 286 R991.
    View related products by Pharmacological Action or by Research Area

    Keywords: Devazepide, Peptides (Gastrointestinal), Selective, Orally Active CCK1 Receptor Antagonist, L-364,718, MK 329, Tocris Bioscience

    New Product Guide
    Tocris Bioscience. Our latest New Product Guide highlights over 140 new productsOur latest New Product Guide highlights over 140 new products.
    Request Copy / View PDF
    Our laboratory loves dealing with Tocris and consider many of the compounds you sell to be far better quality than the compounds that we have received from other companies. Once again, thank you very much..”
    Researcher, Albany Medical College, USA
    New Products in this Area

     3007Apelin-17 (human, bovine)
     Endogenous APJ receptor agonist
     3008Galanin (porcine)
     Galanin receptor agonist
     2951[Des-octanoyl]-Ghrelin (rat)
     Major circulating form of ghrelin; devoid of activity at GHS receptor
     3006Gastrin I (human)
     Selective CCK2 agonist
     2607CI 988
     Potent and selective CCK2 antagonist
     2608PD 135158
     Potent and selective CCK2 antagonist
     2711Bay 55-9837
     Potent and selective VPAC2 agonist
     2699AR-M 1896
     Selective GalR2 agonist
     1524LY 288513
     Selective CCK2 antagonist
     2698M871
     Selective GalR2 antagonist
     2697M617
     Selective GalR1 agonist
     2696Galanin (1-29) (rat, mouse)
     Non-selective galanin receptor agonist
     2190SR 27897
     Potent and selective CCK1 antagonist
     2261L-692,585
     Potent, non-peptide GHS receptor agonist
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account