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Category: Ion ChannelsarrowPotassium ChannelsarrowCa2+-Activated Potassium Channels
Cat.No. Product Name
0674 Dequalinium dichloride  
Price and Availability

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Dequalinium dichloride
Chemical Name: 1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride

Biological Activity:

A potent and selective non-peptide blocker of the apamin-sensitive small conductance Ca2+-activated K+ channel (IC50 = 1.1 μM).

Technical Data:

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M.Wt: 527.58
Formula: C30H40Cl2N4
Storage: Store at RT
Solubility: Soluble to 10 mM in Water
CAS No: [522-51-0]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
    Product/Material Safety Data Sheet: View current batch

    References:

    Dunn (1994) Dequalinium, a selective blocker of the slow afterhyperpolarization in rat sympathetic neurones in culture. Eur.J Pharmacol. 252 189.
    View related products by Pharmacological Action or by Research Area

    Keywords: Dequalinium Dichloride, Potassium Channels, K+ Channel Blocker (SKCa), Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
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