DPPE Fumarate | Histamine Receptors | Inhibitor Of Histamine Binding At The Intracellular Binding Site

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Cat.No.	Product Name
0743	DPPE fumarate

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DPPE fumarate

Chemical Name: N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine fumarate

Biological Activity:

Binds with high affinity to the anti-estrogen binding site but not to the estrogen receptor. An inhibitor of histamine binding at the intracellular histamine (H_lc) site.

Technical Data:

M.Wt:	399.49
Formula:	C₁₉H₂₅NO.C₄H₄O₄
Storage:	Desiccate at -20°C
Solubility:	Soluble in Water

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References:

Brandes and Hermonat (1984) A diphenylmethane derivative specific for the antiestrogen binding site found in rat liver microsomes. Biochem.Biophys.Res.Comm. 123 724. Brandes et al (1990) Histamine as an intracellular messenger. Biochem.Pharmacol. 40 1677. Sturman et al (1994) Modulation of the intracellular and H₃-histamine receptors and chemically-induced seizures in mice. Agents Actions 41 C68.

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Keywords: DPPE Fumarate, Histamine Receptors, Inhibitor Of Histamine Binding At The Intracellular Binding Site, Tocris Bioscience

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