Potent
and selective A1 adenosine receptor antagonist, both in vitro and in
vivo. Ki values are 3.9, 130, 50 and 4000 nM for human A1,
A2A, A2B and A3 receptors respectively.
Brunset al (1987) Binding of the A1-selective adenosine
antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes.
Naunyn-Schmied.Arch.Pharmacol. 335 59. Von der Leyen (1989)
Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective
adenosine receptor antagonist, on force of contraction in guinea-pig atrial and
ventricular cardiac preparations. Naunyn-Schmied.Arch.Pharmacol. 340
204. Klotz (2000) Adenosine receptors and their ligands.
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