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Category:
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Enzyme-Linked Receptors Receptor Tyrosine Kinases (RTKs)PDGFR
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Cat.No.
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Product Name
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1222 |
DMPQ dihydrochloride
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Price and Availability
Click here for full price details of
DMPQ dihydrochloride
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Chemical Name:
5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride |
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Biological Activity:
A potent and selective inhibitor of human vascular β-type platelet derived growth factor receptor tyrosine
kinase (β-type PDGFR tyrosine
kinase) (IC50 = 80 nM). Displays > 100-fold selectivity over EGFR
tyrosine kinase, erbB2, p56, protein kinase A and protein kinase C.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Dolle et al (1994) 5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a
potent and selective inhibitor of human vascular β-type platelet-derived
growth factor receptor tyrosine kinase. J.Med.Chem. 37 2627.
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or by Research Area
Keywords: DMPQ Dihydrochloride, Receptor Tyrosine Kinases (RTKs), Potent, Selective Inhibitor Of B-type PDGFRTK, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
Product Feature
Kinase Inhibitors
Key kinase Inhibitors available from Tocris include:
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