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Category:
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7TM Receptors Acetylcholine (Muscarinic) ReceptorsAntagonists
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Cat.No.
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Product Name
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2096 |
DAU 5884 hydrochloride
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Price and Availability
Click here for full price details of
DAU 5884
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Chemical Name:
8-Methyl-8-azabicyclo-3-endo[3.2.1]oct-3-yl-1,4-dihydro
-2-oxo-3(2H)-quinazolinecarboxylic acid ester
hydrochloride |
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Biological Activity:
Selective muscarinic M3 receptor
antagonist. In bovine tracheal smooth muscle, inhibits methacholine-dependent
effects on cell proliferation and muscle contractility.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Doods et al (1993) Characterization of muscarinic receptors in guinea-pig
uterus. Eur.J.Pharmacol. 250 223. Roffel et al
(1993) Cholinergic contraction of the guinea pig lung strip is mediated by
muscarinic M2-like receptors. Eur.J.Pharmacol. 250
267. Gosens et al (2003) Muscarinic M3-receptors
mediate cholinergic synergism of mitogenesis in airway smooth muscle.
Am.J.Respir.Cell Mol.Biol. 28 257. Gosens et al (2004)
Muscarinic M3 receptor-dependent regulation of airway smooth muscle
contractile phenotype. Br.J. Pharmacol. 141 943.
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View related products by Pharmacological Action
or by Research Area
Keywords: DAU 5884, Acetylcholine (Muscarinic) Receptors, M3 Receptor Antagonist, DAU5884, Tocris Bioscience
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Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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