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Category:
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Cellular Processes and Components Other Signal TransductionProtein translocation/Exocytosis/Endocytosis
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Biological Activity:
Endocytosis
inhibitor that blocks the interaction of dynamin with amphiphysin 1 and 2.
Impairs AMPA receptor cycling and blocks DHPG-induced long term depression
(LTD).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Wigge
and McMahon (1998)
The amphiphysin family of proteins and their role in endocytosis at the
synapse. Trends Neursci. 21 339. Lüscher et al
(1999) Role of AMPA receptor cycling in synaptic transmission and plasticity.
Neuron 24 649. Xiao et al (2001) Metabolic
glutamate receptor activation causes a rapid redistribution of AMPA receptors.
Neuropharmacology 41 664.
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View related products by Pharmacological Action
or by Research Area
Keywords: D15, Other Signal Transduction, Endocytosis Blocker, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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