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Category: EnzymesarrowPhosphodiesterases
Cat.No. Product Name
1692 Cilostazol
Price and Availability

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Cilostazol
Chemical Name: 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro -2(1H)-quinolinone

Biological Activity:

Potent phosphodiesterase III A (PDE3A) inhibitor (IC50 = 0.2 μM) and inhibitor of adenosine uptake. Has antimitogenic, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.

Technical Data:

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M.Wt: 369.47
Formula: C20H27N5O2
Storage: Store at RT
Solubility: Soluble to 10 mM in Ethanol and to 50 mM in DMSO
Purity: >99%
CAS No: [73963-72-1]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part I: effects on the central nervous system. Arzneim.-Forsch. 35 1157. Shintani et al (1985) General pharmacological properties of cilostazol, a new antithrombotic drug. Part II: effects on the peripheral organs. Arzneim.-Forsch. 35 1163. Schror (2002) The pharmacology of cilostazol. Diabetes Obes.Metab. 4 S14.
    View related products by Pharmacological Action or by Research Area

    Keywords: Cilostazol, Phosphodiesterases, PDE3A Inhibitor. Also Adenosine Uptake Inhibitor, Tocris Bioscience

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