3a-[(4-Chlorophenyl)phenylmethoxy] Tropane Hydrochloride | Neurotransmitter Transporters | Dopamine Uptake Inhibitor | 3a[(4-Chlorophenyl)phenylmethoxy] Tropane Hydrochloride

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Cat.No.	Product Name
0917	3a-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride

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3a-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride

Biological Activity:

This cocaine analogue binds with high affinity to the dopamine transporter (K_i = 30 nM) and blocks re-uptake of dopamine. However, it is a weak psychomotor stimulant and does not substitute for cocaine in addicted rats.

Technical Data:

M.Wt:	378.34
Formula:	C₂₁H₂₄CINO.HCl
Storage:	Store at RT
Solubility:	Soluble to 75 mM in DMSO

Resources:

Certificate of Analysis / MSDS:

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References:

Newman et al (1994) Novel 3α-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioural profiles. J.Med.Chem. 37 2258. Newman et al (1995) Novel 4'-substituted and 4'4''-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors. J.Med.Chem. 38 3933.

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Keywords: 3a-[(4-Chlorophenyl)phenylmethoxy] Tropane Hydrochloride, Neurotransmitter Transporters, Dopamine Uptake Inhibitor , 3a[(4-Chlorophenyl)phenylmethoxy] Tropane Hydrochloride, Tocris Bioscience

Literature in this Area

Scientific Reviews

Dopamine Receptors
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Product Feature

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