Charybdotoxin | Potassium Channels | K+ Channel Blocker (high Conductance, Ca2+-dependent) | ChTx

Category:

Ion Channels

Potassium Channels

Ca2+-Activated Potassium Channels

Cat.No.

Product Name

1087

Charybdotoxin

Alternative name(s):

ChTx

Price and Availability

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Charybdotoxin

Biological Activity:

Specific inhibitor of the high conductance Ca²⁺-activated K⁺ channel.

Technical Data:

M.Wt:	4295.95
Formula:	C₁₇₆H₂₇₇N₅₇O₅₅S₇
Storage:	Desiccate at -20°C
CAS No:	[95751-30-7]

Resources:

Certificate of Analysis / MSDS:

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References:

Miller et al (1985) Charybdotoxin, a protein inhibitor of single Ca²⁺ activated K⁺ channels from mammalian skeletal muscle. Nature 313 316. Gimenez-Gallego et al (1988) Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium activated potassium channels. Proc.Natl.Acad.Sci.USA 85 3329. Asano et al (1993) Charybdotoxin-sensitive K⁺ channels regulate the myogenic tone in the resting state of arteries from spontaneously hypertensive rats. Br.J.Pharmacol. 108 214.

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Keywords: Charybdotoxin, Potassium Channels, K+ Channel Blocker (high Conductance, Ca2+-dependent), ChTx, Tocris Bioscience

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