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Category: 7TM ReceptorsarrowDopamine ReceptorsarrowD2-like ReceptorsarrowAgonists
Cat.No. Product Name
2193 Carmoxirole hydrochloride
Alternative name(s): EMD 45609
Price and Availability

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Carmoxirole
Chemical Name: 3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-in dole-5-carboxylic acid hydrochloride

Biological Activity:

Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradrenaline release and sympathetic activation. Displays antihypertensive properties in vivo.

Technical Data:

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M.Wt: 410.94
Formula: C24H26N2O2.HCl
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in DMSO
Purity: >98%
CAS No: [98323-83-2]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Hasse et al (1991) Neurochemical profile of EMD 45609 (carmoxirole), a dopamine DA2-receptor agonist. Naunyn-Schmied.Arch.Pharmacol. 343 588. Haeusler et al (1992) Pharmacological basis for antihypertensive therapy with a novel dopamine agonist. Eur.Heart J. 13 129. Rump et al (1993) Dopamine receptor modulation of noradrenaline release by carmoxirole in human cortical kidney slices. Eur.J.Clin.Pharmacol. 44 S47.
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    Keywords: Carmoxirole, Dopamine Receptors, Selective, Peripherally Acting D2-like Agonist, EMD 45609, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Dopamine Receptors
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    Purity To Rely On
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