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Category: 7TM ReceptorsarrowAdenosine ReceptorsarrowAntagonists
Cat.No. Product Name
2793 Caffeine
Price and Availability

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Caffeine
Chemical Name: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione

Biological Activity:

Central nervous system stimulant. Antagonist at A1 and A2A adenosine receptors and inhibitor of cyclic nucleotide phosphodiesterases. Mobilises calcium from intracellular stores and inhibits benzodiazepine binding to GABA receptors.

Technical Data:

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M.Wt: 194.19
Formula: C8H10N4O2
Storage: Store at RT
Solubility: Soluble to 100 mM in Water and to 50 mM in DMSO
Purity: >99%
CAS No: [58-08-2]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Nehlig et al (1992) Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res.Brain Res.Rev. 17 139. Fisone et al (2004) Caffeine as a psychomotor stimulant: mechanism of action. Cell.Mol.Life Sci. 61 857.
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    Keywords: Caffeine, Adenosine Receptors, A1 & A2B Antagonist. CNS Stimulant, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Nucleotide & Nucleoside Receptors
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