CCMQ | Ligand-gated Ion Channels | Used To Characterise NR2B-containing NMDA Receptors

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Category:

Ion Channels

Ligand-gated Ion Channels

Glutamate (Ionotropic) Receptors

NMDA Selective

NMDA Site

Agonists

Cat.No.	Product Name
1238	CCMQ

Price and Availability

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CCMQ

Chemical Name: 2-Carboxy-3-carboxymethylquinoline

Biological Activity:

For use in conjunction with [³H]-homoquinolinic acid to characterise NR2B-containing NMDA receptors; selectively inhibits [³H]-homoquinolinic acid binding to non-NMDA sensitive sites.

Technical Data:

M.Wt:	231.21
Formula:	C₁₂H₉NO₄
Storage:	Desiccate at +4°C
Solubility:	Soluble to 100 mM in DMSO and to 100 mM in 1eq. NaOH

Resources:

Certificate of Analysis / MSDS:

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References:

Brown et al (1998) [³H]-Homoquinolinate binds to a subpopulation of NMDA receptors and to a novel binding site. J.Neurochem. 71 1464.

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Keywords: CCMQ, Ligand-gated Ion Channels, Used To Characterise NR2B-containing NMDA Receptors, Tocris Bioscience

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