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Category:
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Nuclear Receptors Glucocorticoid Receptor
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Cat.No.
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Product Name
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2671 |
Budesonide
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Price and Availability
Click here for full price details of
Budesonide
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Chemical Name:
(11b,16a)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypre
gna-1,4-diene-3,20-dione |
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Biological Activity:
Synthetic anti-inflammatory
glucocorticoid that displays chemopreventive activity. Prevents formation of
lung adenomas and adenocarcinomas in mice following inhalation or oral
administration. Reverse DNA hypomethylation and modulates expression of cancer
related genes.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Spencer et
al (1995) Budesonide. A review of its pharmacological properties and
therapeutic efficacy in inflammatory bowel disease. Drugs 50 854.
Pereira et al (2006) Modulation by budesonide of DNA methylation
and mRNA expression in mouse lung tumors. Int.J.Cancer 120 1150. Wattenberg
et al (2007) Chemoprevention of pulmonary carcinogenesis by aerosolized
budesonide in female A/J mice. Cancer Res. 57 5489.
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View related products by Pharmacological Action
or by Research Area
Keywords: Budesonide, Glucocorticoid Receptor, Synthetic Glucocorticoid; Anti-inflammatory & Chemopreventive, Tocris Bioscience
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Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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