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Category:
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7TM Receptors Peptides (Cardiovascular)Bradykinin Receptors
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Cat.No.
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Product Name
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2371 |
Bombinakinin M
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| Alternative name(s): |
Maximakinin |
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Price and Availability
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Bombinakinin M
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Biological Activity:
Potent
bradykinin receptor agonist. Highly selective for mammalian arterial smooth
muscle bradykinin receptors, displaying ~ 50-fold greater potency than
bradykinin. Elicits dose-dependent contractile effects in smooth muscle of
guinea pig ileum (EC50 = 4.0 nM).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Lai et al (2001) A novel
bradykinin-related peptide from skin secretions of toad Bombina maxima
and its precursor containing six identicals copies of the final product. Biochem.Biophys.Res.Comm. 286
259. O'Rourke et al (2004) The smooth muscle pharmacology of
maximakinin, a receptor-selective, bradykinin-related nonadecapeptide from the
venom of the Chinese toad, Bombina maxima. Regul.Peptides 121
65. Lee et al (2005) Cloning of bradykinin precursor cDNAs from
skin of Bombina maxima reveals novel bombinakinin M antagonists and a
bradykinin potential peptide. Regul.Peptides 127 207.
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or by Research Area
Keywords: Bombinakinin M, Peptides (Cardiovascular), Potent Bradykinin Receptor Agonist, Maximakinin, Tocris Bioscience
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