(±)-Bisoprolol Hemifumarate | Adrenergic Receptors | B1 Antagonist | Bisoprolol Hemifumarate

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Cat.No.	Product Name
0914	(±)-Bisoprolol hemifumarate

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(±)-Bisoprolol hemifumarate

Chemical Name: (±)-1-[4-[[2-(1-Methylethoxy)ethoxy)methyl]phenoxy]-3-[ (1-methylethyl)amino]-2-propanol hemifumarate

Biological Activity:

A selective β₁-adrenergic antagonist. Has a K_d of 2-3 nM at the β₁ receptor and a β₁/β₂ selectivity of approximately 100-fold.

Technical Data:

M.Wt:	383.48
Formula:	C₁₈H₃₁NO₄.½C₄H₄O₄
Storage:	Store at RT
Solubility:	Soluble to 50 mM in Water
Purity:	>98%
CAS No:	[104344-23-2]

Resources:

Certificate of Analysis / MSDS:

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Product/Material Safety Data Sheet: View current batch

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References:

Kaumann and Lemoine (1985) Direct labelling of myocardial β₁-adrenoceptors. Naunyn-Schmied.Arch.Pharmacol. 331 27. Klockow et al (1986) Studies on the receptor profile of bisoprolol. Arzneim.-Forsch. 36 197. Heible et al (1995) α-and β-Adrenoceptors: from the gene to the clinic. 1. Molecular biology and adrenoceptor subclassification. J.Med.Chem. 38 3415.

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Keywords: (±)-Bisoprolol Hemifumarate, Adrenergic Receptors, B1 Antagonist , Bisoprolol Hemifumarate, Tocris Bioscience

Literature in this Area

Scientific Reviews

Adrenoceptor Pharmacology
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“Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..”

Researcher, University of Aberdeen, UK

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