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Category: 7TM ReceptorsarrowAdrenergic ReceptorsarrowBeta-1 Receptors
Cat.No. Product Name
0906 Betaxolol hydrochloride  
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Betaxolol hydrochloride
Chemical Name: 1-[4-[2-(Cyclopropylmethoxy)ethyl]phenoxy]-3-isopropyla mino-2-propanol hydrochloride

Biological Activity:

Selective β1-adrenoceptor antagonist.

Technical Data:

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M.Wt: 343.89
Formula: C18H29NO3.HCl
Storage: Store at RT
Solubility: Soluble to 50 mM in Water
Purity: >99%
CAS No: [63659-19-8]

Resources:

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    References:

    Merck Index 12 1229. Beresford and Heel (1986) Betaxolol. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension. Drugs 31 6. Satoh et al (1993) The affinity of betaxolol, a β1-adrenoceptor-selective blocking agent, for β-adrenoceptors in the bovine trachea and heart. Br.J.Pharmacol. 108 484. Setoguchi et al (1995) Inhibitory action of betaxolol, a β1-selective adrenoceptor antagonist, on voltage-dependent calcium channels in guinea pig artery and vein. Br.J.Pharmacol. 115 198.
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    Keywords: Betaxolol Hydrochloride, Adrenergic Receptors, Selective B1 Antagonist , Tocris Bioscience

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