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Category:
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Cellular Processes and Components ApoptosisBcl2 Family
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Cat.No.
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Product Name
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2160 |
Bax channel blocker
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Price and Availability
Click here for full price details of
Bax channel blocker
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Chemical Name:
3,6-Dibromo-a-(1-piperazinylmethyl)-9H-carbazole-9-etha
nol dihydrochloride |
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Biological Activity:
Potent inhibitor of Bax-mediated mitochondrial cytochrome c
release (IC50 = 0.52 μM). Suggested to inhibit
Bax channel formation/activity.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Bombrun et al (2003) 3,6-Dibromocarbazole piperazine derivatives
of 2-propanol as first inhibitors of cytochrome c release via Bax
channel modulation. J.Med.Chem. 46 21.
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View related products by Pharmacological Action
or by Research Area
Keywords: Bax Channel Blocker, Apoptosis, Inhibits Bax-mediated Mitochondrial Cytochrome C Release, Baxchannel Blocker, Tocris Bioscience
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Literature in this Area Cancer Research Guide | Our unique collection of more than 300 products related to cancer research, including the very latest exclusive research tools. | | Request Copy / View PDF |
| “Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..” Researcher, University of Aberdeen, UK |
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