BRL 37344, Sodium Salt | Adrenergic Receptors | B3 Agonist | BRL37344, Sodium Salt

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Cat.No.	Product Name
0948	BRL 37344, sodium salt

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BRL 37344, sodium salt

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Chemical Name: (R*,R*)-(±)-4-[2-[(2-(3-Chlorophenyl)-2-hydroxyethyl)am ino]propyl]phenoxyacetic acid, sodium salt

Biological Activity:

Potent and selective β₃ adrenoceptor agonist (K_i values are 287, 1750 and 1120 nM for β₃, β₁ and β₂ receptors respectively).

Technical Data:

M.Wt:	385.82
Formula:	C₁₉H₂₁NO₄ClNa
Storage:	Store at RT
Solubility:	Soluble to 100 mM in Water
Purity:	>98%
CAS No:	[127299-93-8]

Resources:

Certificate of Analysis / MSDS:

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References:

Arch et al (1984) Atypical β-adrenoceptor on brown adipocytes as target for anti-obesity drugs. Nature 309 163. Strosberg and Pietri-Rouxel (1996) Function and regulation of the β₃-adrenoceptor. TiPS 17 373. Ayo Oriowo et al (1996) The selectivity in vitro of the sterioisomers of the beta-3 adrenoreceptor agonist BRL 37344. J.Pharmacol.Exp.Ther. 277 22. Board et al (2000) BRL37344, but not CGP12177, stimulates fuel oxidation by soleus muscle in vitro. Eur.J.Pharmacol. 406 33.

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Keywords: BRL 37344, Sodium Salt, Adrenergic Receptors, B3 Agonist, BRL37344, Sodium Salt, Tocris Bioscience

Literature in this Area

Scientific Reviews

Adrenoceptor Pharmacology
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