BD 1047 Dihydrobromide | Sigma & Imidazoline | S1 Selective Antagonist | BD1047 Dihydrobromide

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Cat.No.	Product Name
0956	BD 1047 dihydrobromide

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BD 1047 dihydrobromide

Chemical Name: N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylami no)ethylamine dihydrobromide

Biological Activity:

σ₁ receptor antagonist, exhibiting a similar binding profile to that of BD 1063 (0883) but with higher affinity (approximately 10-fold) at both σ₁ and σ₂ sites.

Technical Data:

M.Wt:	437.04
Formula:	C₁₃H₂₀CI₂N₂.2HBr
Storage:	Desiccate at +4°C
Solubility:	Soluble to 50 mM in Water
Purity:	>99%
CAS No:	[138356-20-4]

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Certificate of Analysis / MSDS:

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References:

Matsumoto et al (1995) Characterisation of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism. Eur.J.Pharmacol. 280 301. Garrone et al (2000) Effects of trazodone on neurotransmitter release from rat mossy fibre cerebellar synaptosomes. Eur.J.Pharmacol. 400 35. Romieu et al (2000) Involvement of the sigma1 receptor in the cocaine-induced conditioned place preference. Neuroreport 11 2885.

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Keywords: BD 1047 Dihydrobromide, Sigma & Imidazoline, S1 Selective Antagonist, BD1047 Dihydrobromide, Tocris Bioscience

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