B-HT 920 | Dopamine Receptors | D2 Receptor Agonist. Also A2 Agonist & 5-HT3 Antagonist | Talipexole | BHT 920

Category:

7TM Receptors

Dopamine Receptors

D2-like Receptors

D2-selective

Cat.No.

Product Name

2759

B-HT 920

Alternative name(s):

Talipexole

B-HT 920 C10H15N3S.2HCl 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-amine dihydrochloride

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B-HT 920

Chemical Name: 5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d] azepin-2-amine dihydrochloride

Biological Activity:

Dopamine D₂ receptor agonist, α₂-adrenoceptor agonist and 5-HT₃ receptor antagonist. Displays antiParkinsonian activity.

Technical Data:

M.Wt:	282.23
Formula:	C₁₀H₁₅N₃S.2HCl
Storage:	Desiccate at RT
Solubility:	Soluble to 100 mM in Water and to 100 mM in DMSO
Purity:	>98%
CAS No:	[36085-73-1]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Robertson et al (1993) In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release. J.Pharmacol.Exp.Ther. 264 1344. Nishio et al (1996) 5-HT₃ receptor blocking properties of the antiParkinsonian agent, talipexole. Gen.Pharmacol. 27 779. Ricci and Taira (1999) Adrenoceptor involvement in the cardiovascular responses to B-HT 920 in sinoaortic denervated rats. Gen.Pharmacol. 32 29.

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Keywords: B-HT 920, Dopamine Receptors, D2 Receptor Agonist. Also A2 Agonist & 5-HT3 Antagonist, Talipexole, BHT 920, Tocris Bioscience

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Dopamine Receptors
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