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Anti-phospho-GluR1 (S831) phosphorylated blocking peptide
Biological Activity:
Synthetic peptide (LIPQQ(pS)INEAI[K])
corresponding to amino acids 826-836 of rat mature GluR1 (Accession No.
P19490), with a phosphorylated serine at position 831, and a lysine added to
the C-terminus for conjugation. Immunogen used for anti-phospho-GluR1 (Ser831)
(Cat. No. 2041).
Displays 26-fold and > 440-fold selectivity over kainate and NMDA receptors respectively. Neuro-protective; delays neuronal death in a global ischaemia model and cerebral infarction in a focal ischaemia model.