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Anti-GluR4 blocking peptide
Biological Activity:
Synthetic peptide ([K]-HTGTAIRQSSGLAVIASDLP)
corresponding to the C-terminal amino acids 883-902 of rat precursor GluR4
(Accession No. P19493) with a lysine added at the N-terminus of the peptide.
Immunogen used for anti-GluR4 (Cat. No. 2046).
Displays 26-fold and > 440-fold selectivity over kainate and NMDA receptors respectively. Neuro-protective; delays neuronal death in a global ischaemia model and cerebral infarction in a focal ischaemia model.