Amyloid B-peptide (1-42) (human) | Cell Metabolism | Predominant Amyloid B-protein Fragment

Category:

Cat.No.	Product Name
1428	Amyloid b-Peptide (1-42) (human)

Price and Availability

Click here for full price details of
Amyloid b-peptide (1-42) (human)

Biological Activity:

Human form of the predominant amyloid β-peptide found in the brains of patients with Alzheimer's disease. Downregulates bcl-2 and increases the levels of bax. Neurotoxic.

Technical Data:

M.Wt:	4514.08
Formula:	C₂₀₃H₃₁₁N₅₅O₆₀S
Storage:	Desiccate at -20°C
CAS No:	[107761-42-2]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Glenner and Wong (1984) Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem.Biophys.Res.Comm. 120 885. Paradis et al (1996) Amyloid beta peptide of Alzheimer's disease downregulates bcl-2 and upregulates bax expression in human neurons. J.Neurosci. 16 7533. Van Nostrand et al (1996) Amyloid β-protein induces the cerebrovascular cellular pathology of Alzheimer's disease and related disorders. Ann.N.Y.Acad.Sci. 777 297.

View related products by Pharmacological Action or by Research Area

Keywords: Amyloid B-peptide (1-42) (human), Cell Metabolism, Predominant Amyloid B-protein Fragment, Tocris Bioscience

Literature in this Area

Signal Transduction Guide

	A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
View PDF

Spring Specials

25% discount* on
selected Tocris products including:

Potent & selective NOP antagonist
Blocker of retinoic acid metabolism
Potent CCR1 receptor antagonist
Selective GnRH receptor antagonist
NMDA receptor antagonist

*Terms and conditions

New Products in this Area

	2784	Acipimox
	Antilipolytic agent
	2756	Arachidonic acid (in Tocrisolve^TM 100)
	Endogenous free fatty acid (in water-soluble emulsion)
	2567	PLP (139-151)
	Encephalitogenic myelin proteolipid fragment
	2568	MOG (35-55)
	Encephalitogenic myelin oligodendrocyte glycoprotein fragment

for new product e-alerts

User ID
Password