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Category:
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Enzymes Glycosylases
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Cat.No.
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Product Name
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2673 |
Acarbose
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| Alternative name(s): |
Bay-g 5421 |
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Price and Availability
Click here for full price details of
Acarbose
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Chemical Name:
O-4,6-Dideoxy-4-[[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hyd
roxymethyl)-2-cyclohexen-1-yl]amino]-a-D-glucopyranosyl
-(1-4)-O-a-D-glucopyranosyl-(1-4)-D-Glucose |
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Biological Activity:
Inhibitor of intestinal α-glucosidase
(IC50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex
carbohydrates.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Krause et al
(1982) Inhibition of disaccharide digestion in rat intestine by the
alpha-glucosidase inhibitor acarbose (BAY g 5421). Digestion 23
232. Balfour and McTavish (1993) Acarbose: an update of its pharmacology
and therapeutic use in diabetes mellitus. Drugs 46 1025. Oki
et al (2000) Evaluation of alpha-glucosidase inhibition by using an
immobilized assay system. Biol.Pharm.Bull. 23 1084.
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View related products by Pharmacological Action
or by Research Area
Keywords: Acarbose, Glycosylases, Glucosidase A Inhibitor (intestinal), Bay-g 5421, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
Purity To Rely On
When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.
Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.
This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
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