ARC 239 Dihydrochloride | Adrenergic Receptors | A2B Antagonist | ARC239 Dihydrochloride

Category:

Cat.No.	Product Name
0928	ARC 239 dihydrochloride

Price and Availability

Click here for full price details of
ARC 239 dihydrochloride

Other Information:

Sold with the permission of Boehringer Ingelheim GmbH

Chemical Name: 2-[2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl]-4,4-dime thyl-1,3-(2H,4H)-isoquinolindione dihydrochloride

Biological Activity:

Selective α_2B adrenoceptor antagonist (pK_D values are 8.8, 6.7 and 6.4 at α_2B, α_2A, and α_2D receptors respectively).

Technical Data:

M.Wt:	480.43
Formula:	C₂₄H₂₉N₃O₃.2HCl
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO and to 100 mM in Water
Purity:	>98%
CAS No:	[67339-62-2]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Bylund et al (1988) Alpha-2A and alpha-2B adrenergic subtypes: antagonist binding in tissues and cell lines containing only one subtype. J.Pharmacol.Exp.Ther. 245 600. Fuder and Selback (1993) Characterisation of sensory neurotransmission and its inhibition via α_2B-adrenoceptors and via non-α₂ adrenoceptors in rabbit iris. Naunyn.Schmied.Arch.Pharmacol. 347 394.

View related products by Pharmacological Action or by Research Area

Keywords: ARC 239 Dihydrochloride, Adrenergic Receptors, A2B Antagonist , ARC239 Dihydrochloride, Tocris Bioscience

Literature in this Area

Scientific Reviews

Adrenoceptor Pharmacology
Download PDF

Unique & Diverse Compound Libraries

Tocriscreen Collections : For pricing and compound information click here

Fully annotated small molecule libraries for HTS, HCS and
chemical biology applications.

1120 compounds
Pre-dissolved in DMSO

Tocriscreen Total (250 μL/well)
Tocriscreen Mini (50 μL/well)

New Products in this Area

	2964	Doxazosin mesylate
	α₁-adrenoceptor antagonist
	1051	Zinterol hydrochloride
	Selective β₂ agonist
	2958	DSP-4
	Adrenergic neurotoxin
	2838	(R)-(-)-Phenylephrine hydrochloride
	α₁-adrenoceptor agonist
	2806	Alprenolol hydrochloride
	β antagonist
	2398	SNAP 5089
	Subtype selective α_1A-adrenoceptor antagonist
	2638	ST 91
	α₂ agonist, putative α_2C agonist
	2685	Carvedilol
	β-adrenoceptor and α₁-adrenoceptor antagonist
	2658	Bucindolol
	β₁- and β₂-adrenoceptor antagonist
	2666	JP 1302 dihydrochloride
	Potent and selective α_2C antagonist
	1811	Modafinil
	Psychostimulant

for new product e-alerts

User ID
Password