(+)-AJ 76 Hydrochloride | Dopamine Receptors | Antagonist; Preferential Action At D2-like Autoreceptors | AJ76 Hydrochloride

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Cat.No.	Product Name
0678	(+)-AJ 76 hydrochloride

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(+)-AJ 76 hydrochloride

Chemical Name: (1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetrali n hydrochloride

Biological Activity:

Dopamine receptor antagonist with preferential action at presynaptic receptors.

Technical Data:

M.Wt:	269.81
Formula:	C₁₅H₂₃NO.HCl
Storage:	Store at RT
Solubility:	Soluble to 10 mM in Water
CAS No:	[85379-09-5]

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References:

Johansson et al (1987) Resolved cis and trans-2-amino-5-methoxy-1-methyltetralins: central dopamine receptor agonists and antagonists. J.Med.Chem. 30 602. Kullingsjo et al (1991) Effects of repeated administration of the preferential dopamine autoreceptor antagonist, (+)-AJ76, on locomotor activity and brain DA metabolism in the rat. Eur.J.Pharmacol. 205 241. Waters et al (1994) Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and metabolism in vivo. Eur.J.Pharmacol. 251 181.

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Keywords: (+)-AJ 76 Hydrochloride, Dopamine Receptors, Antagonist; Preferential Action At D2-like Autoreceptors , AJ76 Hydrochloride, Tocris Bioscience

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